Phase 2 detoxification involves the elimination of unwanted substances from the body through converting them into water-soluble chemicals that are excreted via bile and urine. Nutrients like B vitamins, vitamin E, folic acid, glutathione and other antioxidants contained in Vetri Liver Canine support the process of eliminating free radicals and detoxifying harmful substances. If excessive, those radicals can damage liver cells. A drawback is that free radicals are produced during this process. The liver converts toxins like hormones, drugs, pesticides, pollutants etc. Phase 1 detoxification involves the neutralizing of unwanted chemicals. What are Phase 1 and Phase 2 detoxification processes? Vetri Liver Canine Bite-sized Chews are designed to support liver health and detoxification functions in dogs.